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Name : leuS (TM0168) Accession : NP_227983.1 Strain : Thermotoga maritima MSB8 Genome accession: NC_000853 Putative virulence/resistance : Unknown Product : leucyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG0495 EC number : - Position : 173980 - 176454 bp Length : 2475 bp Strand : + Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl DNA sequence : ATGAAGGAATACAGACCACAGGAAATAGAGAAAAAATGGCAGGAAGTATGGGAAGAAAAGAAGGTCTTCTATACACCTCA GAGGTCTGAGAAACCCAAGTATTATGCCCTCGTGATGTTTCCGTATCCCTCTGGAACTCTCCACGTAGGGCACGTGAAAA ACTACGTCATAGGTGACATAGTTGCAAGATACAAGAGGATGAGAGGATACAACGTCCTTCACCCGTTCGGATACGACGCA TTCGGACTTCCCGCCGAGAACGCCGCGATCGAAAAGGGAATTCATCCTGAAGAGTGGACAAGGAAGAACATTGCCACCAT TCGGCAGCAGGTGAAAAAACTCGGTATAAGCTACGACTGGAGCAGAGAAATAGCGACCTGCGACGAGGAGTACTACAAGT GGACCCAGTGGATATTTCTCCAGCTCTACAAGAATGGTTTGGCCTACAAGAAAAAGGCGGCTGTCAACTGGTGCCCCAAG TGTAAAACTGTTCTTGCGAACGAGCAGGTGAAAGACGGAAAATGTGAAAGATGTGGAACGAGCGTCACCATAAGGCACCT CGAACAGTGGTTTTTCAAGATCACGGATTACGCGGAAAGACTGCTGAACGACCTGGACAAGCTCACAGGATGGCCGGAGC ACGTCAAGACCATGCAGAGAAACTGGATAGGAAAGAGCACCGGTGCGGAAATAGATTTTCCTGTCGAAGGATCGGATACA AAGATCAGGGTCTTCACAACCAGGCCCGACACACTCTGGGGTGTCACTTTCATGGCTCTTGCACCGGAGTCTCCCCTTGT TGAAGAGCTCGTTCCTGAGGAGAAGAAAGAAGAGCTTCAGGAATTCCTTGAACGTGTAAAGCAGCAGGATAGATTCAGAA GAACCTCTGTCGAAGCCGAGAAAGAAGGGTTCTTCCTGGGAAGGTACGCCATAAACCCCGTGACCGGCGAGAGGATACCG ATCTACGTGGCAAACTACATCCTCATGGAGTATGGAACGGGTGCCATCATGGGAGTTCCTGCCCACGATCAGAGGGACTT CTCCTTCGCTAAAAAATACGGAATTCCGATAAAGGTTGTGATTAAACCAGCAGACAAAGATCTCGATCCGGAGAAGATGG AAGAAGCCTACGAAGGCGAGGGTATCATGGTGAACTCCGGACCGTTCGATGGAACACCGAGCAGCGAAGGAATAGAAAAA GTCATAAATTGGCTCGAGGAAAAAGGCATTGGAAAGAGGTCGGTCCAGTACAAGTTGAGAGACTGGCTCATATCGAGGCA GAGATACTGGGGCGCTCCAATCCCCATCATCTACTGTGAAAAATGCGGTGTTGTACCCGTTCCAGAAGAGGACCTTCCCG TGAGACTTCCAAAAGACGTGGAATTCCTTCCAACGGGTCAATCTCCTCTTTCTTTCCACGAAGGTTTCAAGAAGACAAAG TGCCCCGTCTGTGGCGGAGAAGCCCAGAGAGAAACGGACACCATGGACACTTTCGTTGATTCTTCCTGGTACTTCCTCAG ATACGTGAATCCTCACCTGGAGGATAAGCCGTTCGAGCCTGATGACGTGAACTACTGGTTACCGGTGGATCAGTACATTG GAGGAGTGGAACACGCCGTACTGCATTTGCTGTACTCCAGATTCGTAACCAAGGTACTGCACGATCTGGGTTATCTCAAT TTCGACGAACCATTCACCAACCTTTTCACACAGGGAATGATTTACAAAGACGGTGCCAAGATGTCCAAGTCGAAGGGGAA CGTGGTGTCCCCGGATGAGATGATAGAGAAATACGGTGCGGATACCTTGAGAATGTACATACTCTTCATGGCACCTCCAG AGAAAGACGCCGAATGGAGTGACGCCGGTATCGAAGGTGTTCACAGATTCGTCAAAAGGCTCTGGAACACTTTCTACACG GTTCTTCCGTTTGTGAAAGAAGAAAACACGGAGAATCTTGTGTTGAAAAACTCCACAGAAAAGGAACTCAGAAGAAAGCT TCACAGTATTATCAAGAAGATAACGGAGGATATAGAAGGTGGATTCAAGTTCAACACCGCTATAAGTGGTCTGATGGAAC TCGTGAACCACCTGAGCCAGTACTTGAACAGTGTACCGCAGGAGGAATGGAACAGGAAACTCCTGCGAGAGATAGTAGAG AAACTCACACTCGCTCTTTCACCTTTCGCACCGCACCTTGCAGAGGAGTTCTGGCACGATCTCGGAAACGATAGTCTTGT TGTCCAGCAGTCCTGGCCTTCCTACGATCCAAAAGCGCTCGAAGTGGAGGAAGTCGAAATCGCCATCCAGATAAATGGAA AGGTGAGAGACAAAGTGGTTGTGCCTGTGGATATCTCTGAAGAGGATCTGAAGAGGATCGTCCTCGAAAGAGAAAGGGTC AAGGAATACGTCGATGGCAAACCAATAAGGAAATTCATTTACGTGAAGGGAAGAATCGTAAATATCGTGGTATGA Protein sequence : MKEYRPQEIEKKWQEVWEEKKVFYTPQRSEKPKYYALVMFPYPSGTLHVGHVKNYVIGDIVARYKRMRGYNVLHPFGYDA FGLPAENAAIEKGIHPEEWTRKNIATIRQQVKKLGISYDWSREIATCDEEYYKWTQWIFLQLYKNGLAYKKKAAVNWCPK CKTVLANEQVKDGKCERCGTSVTIRHLEQWFFKITDYAERLLNDLDKLTGWPEHVKTMQRNWIGKSTGAEIDFPVEGSDT KIRVFTTRPDTLWGVTFMALAPESPLVEELVPEEKKEELQEFLERVKQQDRFRRTSVEAEKEGFFLGRYAINPVTGERIP IYVANYILMEYGTGAIMGVPAHDQRDFSFAKKYGIPIKVVIKPADKDLDPEKMEEAYEGEGIMVNSGPFDGTPSSEGIEK VINWLEEKGIGKRSVQYKLRDWLISRQRYWGAPIPIIYCEKCGVVPVPEEDLPVRLPKDVEFLPTGQSPLSFHEGFKKTK CPVCGGEAQRETDTMDTFVDSSWYFLRYVNPHLEDKPFEPDDVNYWLPVDQYIGGVEHAVLHLLYSRFVTKVLHDLGYLN FDEPFTNLFTQGMIYKDGAKMSKSKGNVVSPDEMIEKYGADTLRMYILFMAPPEKDAEWSDAGIEGVHRFVKRLWNTFYT VLPFVKEENTENLVLKNSTEKELRRKLHSIIKKITEDIEGGFKFNTAISGLMELVNHLSQYLNSVPQEEWNRKLLREIVE KLTLALSPFAPHLAEEFWHDLGNDSLVVQQSWPSYDPKALEVEEVEIAIQINGKVRDKVVVPVDISEEDLKRIVLERERV KEYVDGKPIRKFIYVKGRIVNIVV |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| leuS | YP_281511.2 | leucyl-tRNA synthetase | Not tested | Not named | Protein | 2e-157 | 44 |
