Gene Information

Name : TM1391 (TM1391)
Accession : NP_229192.1
Strain : Thermotoga maritima MSB8
Genome accession: NC_000853
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease, ATPase subunit
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 1405221 - 1407596 bp
Length : 2376 bp
Strand : +
Note : similar to PID:1001492 percent identity: 73.97; identified by sequence similarity

DNA sequence :
ATGTTCAATCTGGAAGAGTACACGGAAAAGGCGCAGAAAGTAATGATGAGCATTCAGGATATAATGACCCGATACAGACA
AAACCAGCTTTCCAGTGAGCACATACTGCTCGCGATTCTGGAAGAAGGAAACAACGTTGGTGTAGAACTTCTGAAGGAGC
TGAACGTGGATATAAACAGGCTCAAAGATGAGGTGGAGGTGTTCATTGGGAAATACGGGGTTAGAGTCCCTGAAGGAGCA
TCTGTTTCTCAGATTTTCATAACTCCGGACGCGAGGCATGTCATTGAAAAAGCGAGAGAAGAAGCGAGAAGAATGGGAGA
TTCAAAAATAGGAACCGAGCACCTTATTTTGGGGATGGTCCTGTCACCTGATTCCACGGCCTTCCGAATCCTCTCGAGAT
ACGGTGTAACACCTGAGAGAGTCTACGAAGCAATAAGGAAGATCAGATCAACGGGTAAAACAGATGAAGCAGAGAACGTG
GAAGCGCTCGCTCGCTTCACAGTGGATCTCACACAGCTAGCCCGCGAAAAAAAGCTCATGCCTGTAGTGGATCGTGAAAA
GGAAATCAGAAGGGTGATACAGATACTGTCCAGAAGAACGAAGAACAATCCGGTCCTCATAGGAGACCCGGGGGTGGGAA
AGACTGCTGTTGTCGAGGGGCTCGCCCAGAGAATAGTTGAAGGGAAAGTCCCTCTGTTTTTGAGAAACGTCAGAGTCTTG
AAACTCGACATGGGCAGATTGGTGGCAGGGACCCGTTTCAGAGGAGATTTTGAAGAAAGACTGAAACGTCTTCTTGATGA
ATTGAAGAGGAAAAAAGGAGAAGTAATACTCTTCATCGACGAGGTGCACACGGTGGTAGGAGCGGGAGCAGCCGAAGGTG
CTCTCGACGCCGCGAACATAATGAAACCAGAACTCACAACGGGAGAGATTCAGATAATAGGAGCAACCACCGTTGAAGAG
TACAGAAAATACATAGAGAAAGACAGGGCGCTTGAGAGAAGATTCCAGCCGGTCATGGTGGAAGAGCCGACGGTCGAGCA
GACAATTGAAATACTGAAAGGATTAAGAAAGGTCTTTGAAGAACATCATCACGTGAAGATAACGGATGACGCTCTGGAAG
CCGCGGCGAAACTCTCCGCACGATACATAACCAACAGATTCCTCCCGGACAAGGCCGTTGATCTGATAGACGAAGCGGCA
GCGTACGTGCGTCTTGAATCCTCGTACCCTTCAGAAGAACTCCTGAAACTCGAAGAAGAGATCAAAAACCTTGAAGACAA
AATAAACGACGCCGTTGTGAAGGGAGAGTACGAAGAAGCGGCAAAGCTGAAGGTCGAACTCCAGAAATTGAAAAACGAAT
ACGAAGAAAAAAGGAAAAAACAAGAAAAGGTGGAACCGGTTGTCGATGAGAACGTTGTGGCAAAGATCGTGGAACAGTGG
ACCGGCATTCCCGTGTCTCGAATCATGGAATCCGAAAGAGAGAAACTCCTGAAACTCGAAGAATTCATCCACCAGCGCTT
GGTGAATCAGGAGGAAGCCGTGAAGATAGTGGCACGGACCATAAGACGTGCAAGGGTCGGTATCAAGAATCCGAGAAGGC
CCATCGGTGTCTTTCTGTTCCTCGGACCAACGGGCGTGGGAAAGACAGAACTCGCCAGAACTCTCGCAGACGTGCTCTTC
GGCAGCGAAGACGCCATGATCAGGCTCGACATGAGTGAATACATGGAGAAACACTCCGTTGCCAGACTCATAGGAGCACC
TCCGGGTTACGTGGGTTATGAAGAGGGAGGGCAGCTTACCGAGGCTGTGAGAAAAAGGCCTTACAGTGTGATTCTCCTCG
ACGAAATAGAAAAGGCGCATCCAGACGTATTCAACATCCTGCTTCAAGTGTTCGAAGACGGGCGATTGACTGATGGAAAG
GGAAACACCGTGGACTTCAGAAACACCATCATCATCATGACGAGCAACATAGGAAGTGAGAAGATCCTCGAAATGTCGGA
AAACGGTGTGAGAATTGAGATAGAAAAAGAACTGCGAAACACCTTCAAACCCGAGTTCCTGAACAGAATAGACGCCATAG
TTTACTTCAAACCGCTCACGATGGAAGAAGTGAAGAAGATAGTGGAAATCATGGTGAGACAGCTCCAGGAAATACTGAAA
GAGAAGAACATCTCCATCGAGCTTACAGAAAGAGCGAAGGAGTACCTGGCAGAAGCGGGTTACGTGCCATCTCTCGGTGC
AAGACCGCTTCGAAGAATCATAGAACTCGAACTCGAGTCGATGATAGCGGATAAAATACTGGAAGGAGAGATAAAAGAAG
GAGACAGGGTTCTGGTCGACGCGGACGAATACGGTCTGAAGATAGAGAGGAGGTGA

Protein sequence :
MFNLEEYTEKAQKVMMSIQDIMTRYRQNQLSSEHILLAILEEGNNVGVELLKELNVDINRLKDEVEVFIGKYGVRVPEGA
SVSQIFITPDARHVIEKAREEARRMGDSKIGTEHLILGMVLSPDSTAFRILSRYGVTPERVYEAIRKIRSTGKTDEAENV
EALARFTVDLTQLAREKKLMPVVDREKEIRRVIQILSRRTKNNPVLIGDPGVGKTAVVEGLAQRIVEGKVPLFLRNVRVL
KLDMGRLVAGTRFRGDFEERLKRLLDELKRKKGEVILFIDEVHTVVGAGAAEGALDAANIMKPELTTGEIQIIGATTVEE
YRKYIEKDRALERRFQPVMVEEPTVEQTIEILKGLRKVFEEHHHVKITDDALEAAAKLSARYITNRFLPDKAVDLIDEAA
AYVRLESSYPSEELLKLEEEIKNLEDKINDAVVKGEYEEAAKLKVELQKLKNEYEEKRKKQEKVEPVVDENVVAKIVEQW
TGIPVSRIMESEREKLLKLEEFIHQRLVNQEEAVKIVARTIRRARVGIKNPRRPIGVFLFLGPTGVGKTELARTLADVLF
GSEDAMIRLDMSEYMEKHSVARLIGAPPGYVGYEEGGQLTEAVRKRPYSVILLDEIEKAHPDVFNILLQVFEDGRLTDGK
GNTVDFRNTIIIMTSNIGSEKILEMSENGVRIEIEKELRNTFKPEFLNRIDAIVYFKPLTMEEVKKIVEIMVRQLQEILK
EKNISIELTERAKEYLAEAGYVPSLGARPLRRIIELELESMIADKILEGEIKEGDRVLVDADEYGLKIERR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 2e-159 48

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
TM1391 NP_229192.1 ATP-dependent Clp protease, ATPase subunit VFG0080 Protein 4e-136 52
TM1391 NP_229192.1 ATP-dependent Clp protease, ATPase subunit VFG0079 Protein 8e-180 51