Gene Information

Name : TM1379 (TM1379)
Accession : NP_229180.1
Strain : Thermotoga maritima MSB8
Genome accession: NC_000853
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 1396221 - 1397498 bp
Length : 1278 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGATAGATATAAAGCTCATCAGACAAAATCCCGATTTCGTGAAGGAAGCCCTCAGAAAGCGAGGAGAGGATCCCGCTAT
AATCGATGAGATTTTGAAGATCGACGCCGACTGGCGCGCTACCATCACGAAAACCAACGAGCTGAGATCCAGAAGAAACG
AAATTTCCAAAAATGTGGCAAGGTTGAAAAAAGAAGGGAAAAACGCAGAGGCAGAGGCACTCATCGAGGAAGGGAAAAGA
TTAGGAGAAGAGATAAAAGCGTTAGAAGAAAAAGAAAAAGAACTTCAGAAGAAGTTAAACGATCTTCTTTTGATGATTCC
GAACATCCCGCATGAGAGTGTCCCCGTTGGAGAAGACGAATCTCAGAACGTTGAAGTGAGAAGGTGGGGAGAGCCGAGAG
AATTCGACTTCACCCCGCTCGCTCACTGGGACCTCGGACCTGCGTGGGGGCTCATGGATTTCAGCAGGGCGTCCAAGCTC
AGCGGTTCCAGATTCACCGTTATGTATGGAAAACTCGCAAGACTCGAGAGGGCTCTGATAAACTTCATGCTTGACGTTCA
TACAAAGGAACACGGTTACACGGAAGTGTGGGTTCCACACCTGGTGAAAAGAGAAACCATCACCATAACCGGACAGCTCC
CCAAATTCGAAGAAGAGCTTTATCTTGCTGAGAGGGATGACCTGTTCCTCATTCCGACGGCTGAGGTTCCCCTCGCAGCG
CTTCACAGTGGAGAGATCCTCGAAGAGAAAGAACTACCAAAGAAATACGTCTCTTACACTCCCTGTTACCGCAGAGAAGC
GGGAAGTTACGGGAAAGACGTGAGGGGGATGATCAGGCAGCATCAATTCGACAAGGTCGAGCTCGTCTGGGTGACCACAC
CGGAAAGATCCTTCGAAGATCTTGAAGAGCTTGTGAAAGACGCCGAAACCATTCTTAGAAAATTGGAGCTCCCTTACAGA
GTCGTTTCGCTCTGTACGGGAGATCTCGGATTCACCTCCGCGAAAACCTACGATATAGAAGTGTGGCTTCCTTCCTACAA
CGCATACAAAGAGATATCTTCCTGCAGTAACGTGACGGACTTTCAGGCGAGAAGAGGAAACATGAGATACAGAAGGAGAT
CGGATGGAAAGCTCGAATACGTTCACACGTTGAACGGATCGGGTATCGCCGTTGGAAGGGCACTCGTTGCGATACTGGAA
AACTACCAGCAACCAGACGGCAGTGTGAGAGTGCCGGAGGTGCTCGTTCCCTACACAGGGTTCGAGGTGATACCGTAG

Protein sequence :
MIDIKLIRQNPDFVKEALRKRGEDPAIIDEILKIDADWRATITKTNELRSRRNEISKNVARLKKEGKNAEAEALIEEGKR
LGEEIKALEEKEKELQKKLNDLLLMIPNIPHESVPVGEDESQNVEVRRWGEPREFDFTPLAHWDLGPAWGLMDFSRASKL
SGSRFTVMYGKLARLERALINFMLDVHTKEHGYTEVWVPHLVKRETITITGQLPKFEEELYLAERDDLFLIPTAEVPLAA
LHSGEILEEKELPKKYVSYTPCYRREAGSYGKDVRGMIRQHQFDKVELVWVTTPERSFEDLEELVKDAETILRKLELPYR
VVSLCTGDLGFTSAKTYDIEVWLPSYNAYKEISSCSNVTDFQARRGNMRYRRRSDGKLEYVHTLNGSGIAVGRALVAILE
NYQQPDGSVRVPEVLVPYTGFEVIP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 1e-96 53