Gene Information

Name : tktB (CT750)
Accession : NP_220269.1
Strain : Chlamydia trachomatis D/UW-3/CX
Genome accession: NC_000117
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : 2.2.1.1
Position : 881422 - 883422 bp
Length : 2001 bp
Strand : +
Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo

DNA sequence :
ATGGCTGGCAATAGTGATTTAGATATAGACATCTTAGAAAAGATTGCAGGAACTATTAAACAGTTGAGCATAGAAAGTAT
TCAGAAAGCATCTTCAGGTCATCCAGGAATGCCTTTAGGATGCGCAGAGCTCGCTGCTTATTTATATGGTTACGTATTGC
GATATAATTCTAAAGATTCTCGATGGGTGAATAGGGATCGCTTTGTTCTCTCTGCTGGACATGGTTCTGCTCTTCTTTAC
TCTTGTTTGCATTTAGCAGGATTCGATGTAAACCTAGAGGATCTGCAACAATTTCGTCAGCTCCAATCCCGAACTCCCGG
GCATCCAGAATTTAGAGAAACTGATGGTGTAGAAGCCACTACAGGACCTCTAGGACAAGGAGTAGGAAATGCTGTTGGAA
TGGCTCTTTCATTAAAAATGTTAGGAGCCAGATTTAATCAGCCTGCGAATTCTATCTTTGATGCAAAAGTGTATTGCTTA
GCAGGAGATGGGTGCTTCATGGAAGGCGTGAGTCATGAAGCTTGTAGTTTCGCGGGTTCTTTAGGCTTGGATAATCTCGT
TTTGATTTATGATCATAATGAGATTATTTTAGACGGGACTCTTCACGATGTAAGTATTGAGGATACAAAACAGAGATTCT
TAGCATATGGCTGGGATGTGTTTGAAACTGACGGACATGATTTTGAGAGCTTGCATCAGGTTTTCACACAGATCAAGAAA
AGCCAATGCAAACCTACGTTGATTATTGCACATACTATTATTGGACACGGCTCCCCTAAAGAAGGAACCAATAAAGCACA
TGGGTCTCCTTTAGGAGAGGATGGTGTTGCTCAAACTAAAAGTTTCTGGCATCTCCCAGAAGAAAAGTTTTTCGTTCCTT
CGGCAGTGAAGATGTTCTTTGCTGCAAAACAACAGGAAGGTAAGAAATTACAGGAAGAATGGCAAGAACGCTTCCGAGTC
TGGTCTAAACAAGCTCCCGAGCAACATCAAGAATATCTTCGATTGATTCAAGAGATCTCGATTCAAGAACTCGAAGAAAT
TTTGAATCTTATTGATATGCCAGAGTCCATAGCCGGGCGTGCAGCTTCGAATAAAGTCATTCAGGTATTAGCAGAGGATA
TTCCATCCCTCGTAGGGGGATCGGCGGATCTCTCTAGTTCAGATGGTACCTGGATAGCTAAAGAAGGAACTATTAGTGCT
AGCGATTTTCTTGGGCGGAATATTCGCTATGGAGTGCGCGAATTCGGAATGGGCACGATTATGAACGGATTAGCGTATAG
TCAAGTATTCCGTCCTTTTGGGGGAACTTTTTTAGTCTTTTCCGATTATTTGCGTTCCGCGATTCGATTAGCAGCATTAT
CTAAATTGCCGGTAATTTATCAGTTCACTCATGATTCGATTTTTGTTGGAGAGGATGGACCTACACATCAGCCTATAGAG
CAAATCATGTCGCTGCGGGCTATTCCAGGGCTAAGAGTGATTCGTCCTGCGGATGCGAATGAAGTGAAAGGAGCATGGTT
AGCTGCTTTAGAAAGCGCTGGTCCAACAGCGTTAATTTTATCTCGACAAAATCTACCTACTCTTAAAGAGACGAAACGTT
CTTTCAGAGAAGGAGTAAGAAAGGGTGCTTATATTCTGGTTAAAGAGGAAGGAGATCGCCCAGACTATACGCTGTGTGCT
TCTGGATCCGAGGTGCATTTGGCTATAGAGGTTGCACAAAGTCTTATGGCTTTAGATAATCGTGTGCGAGTGATTTCATT
CCCTTGTTGGGAGCTATTCGAGAGACAAGACGTTGAGTATCGCGAATCCGTAATAGGAGGAGATTTAGGGTTGCGTGTTT
CTATAGAAGCAGGTACCGCCTTGGGTTGGTACAAATACATCGGTAGCAATGGCTTAGCCATTGCCATGGATGGGTTTGGA
ATGTCCGGAGCTCCCAATGAGGTGGCAGAGACTTGCGGTTTCACTGTAGATAATATTGTGCAGAGAATCCTTTCTGTTTA
G

Protein sequence :
MAGNSDLDIDILEKIAGTIKQLSIESIQKASSGHPGMPLGCAELAAYLYGYVLRYNSKDSRWVNRDRFVLSAGHGSALLY
SCLHLAGFDVNLEDLQQFRQLQSRTPGHPEFRETDGVEATTGPLGQGVGNAVGMALSLKMLGARFNQPANSIFDAKVYCL
AGDGCFMEGVSHEACSFAGSLGLDNLVLIYDHNEIILDGTLHDVSIEDTKQRFLAYGWDVFETDGHDFESLHQVFTQIKK
SQCKPTLIIAHTIIGHGSPKEGTNKAHGSPLGEDGVAQTKSFWHLPEEKFFVPSAVKMFFAAKQQEGKKLQEEWQERFRV
WSKQAPEQHQEYLRLIQEISIQELEEILNLIDMPESIAGRAASNKVIQVLAEDIPSLVGGSADLSSSDGTWIAKEGTISA
SDFLGRNIRYGVREFGMGTIMNGLAYSQVFRPFGGTFLVFSDYLRSAIRLAALSKLPVIYQFTHDSIFVGEDGPTHQPIE
QIMSLRAIPGLRVIRPADANEVKGAWLAALESAGPTALILSRQNLPTLKETKRSFREGVRKGAYILVKEEGDRPDYTLCA
SGSEVHLAIEVAQSLMALDNRVRVISFPCWELFERQDVEYRESVIGGDLGLRVSIEAGTALGWYKYIGSNGLAIAMDGFG
MSGAPNEVAETCGFTVDNIVQRILSV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 2e-122 44
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 6e-114 44