Gene Information

Name : serS (CT729)
Accession : NP_220248.1
Strain : Chlamydia trachomatis D/UW-3/CX
Genome accession: NC_000117
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 840809 - 842095 bp
Length : 1287 bp
Strand : -
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGTTAGATATACGATTAATACGCAAGGAACCAAAAGAGTGCGAAAGCCGTCTTCAAAAAAAAGATCCCGCTATTTCTTT
AGAACGCCTCCTAGACTTGGATAAAACTGTGCGTCAGTTAAAGGCGGATTCAGAAGCTCTGCTTGCAAAGCGTAAGGTAT
TATCTGGTCAGATTCATAAAGCTAAAGTTGCTAACGAAAATGCTGACGCCTTGATTCAAGAAGTGAATACTATTGCAGAT
CAACTCGTTGCATTTGAAACAACTTTGCAAGAACAGGAAGCACTTCTAGAAGATCTCATGGCGAGACTGCCTAATTATCC
AGATGAAGATGTTCCAGTTTCTCCTGATAAAACAGGAAACCAAGTGATTAAAGGCCACGGTGAGGTACCTACTTTTCCTT
TCCCTCCCAAACACCATATGCAACTTAATGAAGCGTTGCAAATTTTAGACTTTAAACTCCCTGCCAAAACTACAGGGTCT
GGCTGGCCGGCTTATTGTAATGAAGGAGTTCTTCTAGAATGGGCTCTGCTTACTTATCTTCTGAATAAACAGCAAGCACA
TGGCTTTCAATTGTGGCTCCCTCCCTTACTTGTTAAACGAGATATTCTCTTCGGTTCAGGACAAATTCCTAAGTTCGATG
GACAGTATTACCGTGTTGAGGATGGAGATCAGTCTCTTTTCCTTATCCCGACAGCAGAAGTCGTCCTCAATGGATTCCAT
TCTCAAGAAATTCTAAATGAGCAAGATCTCCCTCTCTGTTATGCTGCATTTACTCCCTGCTTCCGCAGAGAGGCTGGCGC
TGGAGGAGCTCACGAACGAGGACTTGTGCGAGTCCATCAGTTCCACAAAGTAGAAATGTTTGCTTTCACTACTCCGGAAC
AAGAAGAAGTTGTCTATCAAAAAATGCTTCATGTTGTGGAAGAAATTCTGTCTGAACTGCAACTCCCCTATCAGCTTTCC
TTACTTTCCACAGGAGACATGTCATTCACTGCTAAGAAAACGATCGATGCAGAAGTGTGGCTCCCAGGACAAAAAGCGTT
CTATGAAGTCTCCTCTATTTCTAAATGCGGAGATTTTCAAGCTCGACGATCCGAAACACGCTATCGAGATGCTCAAGGTA
AATTGCACTTCGTTAACACTCTAAACGGCTCTGGATTGGCAACGCCAAGATTGTTGGTCGCTATTTTAGAAAATTATCAG
CAAGCGGATGGCTCTGTCGTCATTCCTTCTGTTCTTCGCCCCTATATGAATAACCAAGAGATTCTCCTACCCAAAACGGT
AAGATAA

Protein sequence :
MLDIRLIRKEPKECESRLQKKDPAISLERLLDLDKTVRQLKADSEALLAKRKVLSGQIHKAKVANENADALIQEVNTIAD
QLVAFETTLQEQEALLEDLMARLPNYPDEDVPVSPDKTGNQVIKGHGEVPTFPFPPKHHMQLNEALQILDFKLPAKTTGS
GWPAYCNEGVLLEWALLTYLLNKQQAHGFQLWLPPLLVKRDILFGSGQIPKFDGQYYRVEDGDQSLFLIPTAEVVLNGFH
SQEILNEQDLPLCYAAFTPCFRREAGAGGAHERGLVRVHQFHKVEMFAFTTPEQEEVVYQKMLHVVEEILSELQLPYQLS
LLSTGDMSFTAKKTIDAEVWLPGQKAFYEVSSISKCGDFQARRSETRYRDAQGKLHFVNTLNGSGLATPRLLVAILENYQ
QADGSVVIPSVLRPYMNNQEILLPKTVR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 2e-70 43