Gene Information

Name : pykF (CT332)
Accession : NP_219839.1
Strain : Chlamydia trachomatis D/UW-3/CX
Genome accession: NC_000117
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 374217 - 375674 bp
Length : 1458 bp
Strand : +
Note : catalyzes the formation of phosphoenolpyruvate from pyruvate

DNA sequence :
ATGATCGCTAGAACGAAAATTATTTGTACGATAGGCCCTGCAACGAATACCCCTGAGATGCTGGAAAAGCTTCTTGATGC
AGGGATGAATGTAGCTCGCCTTAATTTTAGCCACGGGACCCATGAAAGCCATGGCCGGACCATCGCTATTCTTAAAGAAC
TACGAGAGAAGCGCCAAGTTCCTTTAGCTATTATGCTAGATACAAAAGGTCCCGAAATTCGTTTAGGCCAAGTAGAATCT
CCTATAAAAGTACAGCCTGGGGATCGTCTTACTCTCGTTAGCAAAGAAATTTTAGGATCCAAAGAAAGCGGCGTTACTCT
TTATCCAAGTTGTGTATTCCCTTATGTTAGAGAACGAGCTCCTGTTCTCATTGATGATGGGTATATCCAAGCAGTGGTGG
TCAATGCTCAAGAGCATATGGTGGAAATAGAGTTTCAAAATTCAGGAGAAATAAAATCCAACAAATCTCTTAGCATCAAA
GATATCGATGTTGCTCTTCCTTTCATGACAGAGAAGGATATTGCAGACTTAAAATTTGGGGTAGAACAAGAACTCGATCT
TATCGCTGCTTCGTTCGTCAGATGTAATGAAGATATTGACAGCATGCGTAAAGTTTTGGAAAGCTTTGGTCGTCCTAATA
TGCCCATCATTGCTAAAATAGAAAATCATTTAGGAGTACAAAATTTCCAAGAGATCGCTAGAGCTGCTGATGGTATCATG
ATTGCACGCGGGGATCTTGGTATTGAATTGTCTATTGTTGAAGTTCCTGGACTACAAAAATTTATGGCCCGAGCATCGAG
GGAAACGGGTCGGTTTTGTATCACTGCAACGCAAATGCTCGAGTCAATGATTCGCAACCCCCTTCCTACACGAGCCGAAG
TCTCTGACGTTGCCAACGCCATTTACGATGGAACCTCTGCAGTCATGTTGTCTGGAGAAACTGCCTTAGGAGCCCATCCT
GTACATGCAGTAAAAACAATGCGTTCCATTATCCAAGAGACTGAGAAGACTTTCGATTACCACGCTTTTTTCCAGCTGAA
CGACAAAAACAGCGCTCTCAAAGTTTCTCCTTATCTTGAAGCCATTGGGTTTTCTGGAATCCAAATTGCAGAAAAAGCAT
CTGCCAAAGCCATTATTGTGTATACCCAGACGGGAGGATCTCCGATGTTTTTATCCAAATATCGACCTTATCTCCCTATT
ATTGCTGTTACCCCTAACCGCAATGTGTACTATCGTTTAGCTGTAGAATGGGGAGTATATCCTATGCTAACCCTAGAATC
GAACCGTACAGTCTGGCGTCACCAAGCTTGTGTATATGGAGTAGAAAAAGGAATTCTTTCTAACTATGATAAAATTCTTG
TCTTCAGCCGCGGAGCTGGGATGCAAGACACCAACAATCTCACCTTGACAACTGTGCATGATGTGCTATCCCCCTCTCTT
GACGAGATAGTTCCATAA

Protein sequence :
MIARTKIICTIGPATNTPEMLEKLLDAGMNVARLNFSHGTHESHGRTIAILKELREKRQVPLAIMLDTKGPEIRLGQVES
PIKVQPGDRLTLVSKEILGSKESGVTLYPSCVFPYVRERAPVLIDDGYIQAVVVNAQEHMVEIEFQNSGEIKSNKSLSIK
DIDVALPFMTEKDIADLKFGVEQELDLIAASFVRCNEDIDSMRKVLESFGRPNMPIIAKIENHLGVQNFQEIARAADGIM
IARGDLGIELSIVEVPGLQKFMARASRETGRFCITATQMLESMIRNPLPTRAEVSDVANAIYDGTSAVMLSGETALGAHP
VHAVKTMRSIIQETEKTFDYHAFFQLNDKNSALKVSPYLEAIGFSGIQIAEKASAKAIIVYTQTGGSPMFLSKYRPYLPI
IAVTPNRNVYYRLAVEWGVYPMLTLESNRTVWRHQACVYGVEKGILSNYDKILVFSRGAGMQDTNNLTLTTVHDVLSPSL
DEIVP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 1e-62 43
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 4e-63 43
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 4e-63 43
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 4e-63 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pykF NP_219839.1 pyruvate kinase VFG0479 Protein 2e-63 43