Gene Information

Name : leuS (CT209)
Accession : NP_219713.1
Strain : Chlamydia trachomatis D/UW-3/CX
Genome accession: NC_000117
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 235766 - 238225 bp
Length : 2460 bp
Strand : -
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGCGCTATGATCCCGGTCTCATAGAAGAAAAATGGCAAAAGTTTTGGGAGAACGAGCAAGTTTTTAAGGCTGAGGAGGA
TGAAACTAAAACAAAATACTATGTTTTAGATATGTTTCCTTATCCATCTGGGGCAGGATTGCACGTGGGGCATCTAATTG
GCTATACAGCAACAGATATTGTCGCAAGGTATAAGCGAGCCCAGGGGTTTTCAGTTTTACATCCTATGGGTTGGGATAGT
TTTGGGTTGCCTGCAGAGCAGTATGCTATACGCACGGGGACACACCCAAGAGAGACCACAGAGAAAAACATCGCTAATTT
CAAGAAACAGTTAACTGCAATGGGGTTCTCTTACGACGAAAGTCGAGAGTTCGCTACTTCAGATCCAGAATATTATAAAT
GGACTCAAAAGCTTTTTTTAATCCTTTATGAGAAAGGATTAGCCTATATGGCCGATATGGCTGTTAACTATTGTCCTGAG
TTGGGGACTGTTTTATCGAATGAAGAGATTGAAAACGGATTTTCTGTTGATGGGGGGTATCCTGTTGAAAGGAGAATGCT
TCGCCAATGGGTGCTGCGTATTACAGCATTCGCGGATCAGCTCCTAGAAGGACTAGATGAGCTGGATTGGCCAGAAAGTG
TCAAACAATTGCAGAAGAATTGGATTGGGAAGTCTTCAGGAGCTTCTGTTAATTTTGCCACAGAACATGGAGTAATAGAA
GTTTTCACAACAAGACCGGACACTTTGATAGGAGTTTCTTTTTTAGCCTTAGCTCCTGAACATCCCTTGGTCGATCTCCT
CACTTCTGATGAGCAAAAGGCTGTTGTGGCACAGTATATTAAAGAAACACAAAGTAAAAGCGAAAGAGATCGCATCAGCG
AGATGAAAACTAAGAGCGGGGTCTTTACGGGATCTTACGCAAAACATCCTGTCACTCACAAACTTATCCCTATCTGGATC
GCAGATTATGTATTAATAGGCTTTGGTTCAGGAGCTGTCATGGGAGTTCCTGCTCATGACGAACGTGATTTGCTTTTTGC
CGAACAGTTTAATTTACCTGTAGTCTCCGTGCTTAATAAAGAAGGTGTCTGTATTAATAGCTGTTGTGAAGGGTTCCATT
TGGATGGATTGTCCGGAGAAGAAGCTAAGCAATATGTGATTAACTTTTTAGAAGAGAATCATCTTGGAGCAGCAAAAATC
GCTTATAAGTTGCGAGACTGGCTATTCTCGCGTCAACGTTATTGGGGGGAGCCTATACCGATTATCCATTTTGAAGATGG
CTCTTGTCGTCCTTTAAGAGACTATGAACTTCCATTGTTACCTCCGGAAATTCAAGATTATCGACCAGAAGGGGTCGGAC
AAGGACCTTTGGCTAAGGTGCGAGAGTGGGTACAAGTTTTCGACACGGAGACACAACGAGCTGGGAAACGTGAAACACAT
ACCATGCCTCAATGGGCAGGCTCTTGCTGGTACTATTTACGTTTTTGCGATGCCCACAACTCGGCCGCTCCCTGGGCAAA
GGAAAAGGAACAATATTGGATGCCAGTAGATCTGTATATTGGAGGTGCAGAACATGCTGTACTGCACTTACTTTATGCGC
GTTTCTGGCATCAGGTTTTCTATGAAGCTGGGATTGTTTCAACACCCGAGCCTTTTAAGAAGCTTGTCAATCAAGGCTTG
GTATTGGCGACATCTTATCGCATTCCTGGGAAAGGATATATATATCCTGAAATAGCAAAAGAAGAAAACGGGAAATGGGT
TGCTCCTTCGGGAGAAGAGTTGGATGTCCGTCAAGAAAAGATGTCGAAATCCAAATTAAATGGGGTGGATCCTCAGATCT
TGATAGATGAATTTGGAGCTGACGCTGTTCGGATGTACGCAATGTTTTCAGGGCCTTTAGATAAAAATAAACTCTGGTCT
AACCAAGGAGTTGCTGGTTGCAGACGATTTTTGAATCGTTTTTATGAAATGGTCTCTTCTGATCGAGTTAAGGAAGATAA
CAATTTTGAAGGCTTATCATTAGCGCATAAGCTTGTGCAGCGAGTAACAGATGCTATTGAAAAATTGTCTTTGAATACGA
TACCGTCCTCTTTTATGGAGTTTATCAATGACTTTGTGAAGCTCGCTGTATATCCGAAGAGTGCTGTAGAAATGGCTGTT
CGGGCTTTGGCTCCAATTGCCCCTCACATTAGTGAAGAGTTGTGGGTGTTGTTAGGCAATTCTCCTGGTGTTCAGAAGTC
CGGATGGCCGAGTGTTTTGCCTGAGTATTTAGAAGGACAGACAGTTACTATTGTAGTTCAGGTAAATGGTAAACTTCGAG
CTCGACTAGATATTATGAAGGATGCTTCTAAAGAAGAAGTCCTAGCGTTAGCAAGGGAATCTGCATCTAAGTACTTAGAG
GGGTGTGAAGTGAAAAAGGCTATTTTTGTTCCTGCTCGATTGGTAAACTTTGTTGTATGA

Protein sequence :
MRYDPGLIEEKWQKFWENEQVFKAEEDETKTKYYVLDMFPYPSGAGLHVGHLIGYTATDIVARYKRAQGFSVLHPMGWDS
FGLPAEQYAIRTGTHPRETTEKNIANFKKQLTAMGFSYDESREFATSDPEYYKWTQKLFLILYEKGLAYMADMAVNYCPE
LGTVLSNEEIENGFSVDGGYPVERRMLRQWVLRITAFADQLLEGLDELDWPESVKQLQKNWIGKSSGASVNFATEHGVIE
VFTTRPDTLIGVSFLALAPEHPLVDLLTSDEQKAVVAQYIKETQSKSERDRISEMKTKSGVFTGSYAKHPVTHKLIPIWI
ADYVLIGFGSGAVMGVPAHDERDLLFAEQFNLPVVSVLNKEGVCINSCCEGFHLDGLSGEEAKQYVINFLEENHLGAAKI
AYKLRDWLFSRQRYWGEPIPIIHFEDGSCRPLRDYELPLLPPEIQDYRPEGVGQGPLAKVREWVQVFDTETQRAGKRETH
TMPQWAGSCWYYLRFCDAHNSAAPWAKEKEQYWMPVDLYIGGAEHAVLHLLYARFWHQVFYEAGIVSTPEPFKKLVNQGL
VLATSYRIPGKGYIYPEIAKEENGKWVAPSGEELDVRQEKMSKSKLNGVDPQILIDEFGADAVRMYAMFSGPLDKNKLWS
NQGVAGCRRFLNRFYEMVSSDRVKEDNNFEGLSLAHKLVQRVTDAIEKLSLNTIPSSFMEFINDFVKLAVYPKSAVEMAV
RALAPIAPHISEELWVLLGNSPGVQKSGWPSVLPEYLEGQTVTIVVQVNGKLRARLDIMKDASKEEVLALARESASKYLE
GCEVKKAIFVPARLVNFVV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 0.0 50